Why is ketotifen used?

Ophthalmic ketotifen is used to relieve the itching of allergic pinkeye. Ketotifen is in a class of medications called antihistamines. It works by blocking histamine, a substance in the body that causes allergic symptoms.

Why is Cromolyn no longer available?

The maker of Intal, King Pharmaceuticals, has discontinued manufacturing the inhaled form, cromolyn sodium inhalation aerosol, due to issues involving CFC-free propellant. As stocks are depleted, this inhaler preparation will no longer be available to patients.

Is ketotifen a mast cell stabilizer?

Ketotifen is a mast cell stabilizer used for the management of bronchial asthma and allergic disorders such as atopic dermatitis, allergic rhinitis/conjunctivitis, and chronic urticaria (21-25). Oral ketotifen possesses both anti-mediator and mast cell-stabilizing properties (25).

What is another name for Cromolyn?

BRAND NAME(S): Gastrocrom. USES: This medication is used in people with a food allergy to prevent serious reactions to foods. It is also used to treat and prevent inflammatory bowel diseases (e.g., ulcerative colitis). Cromolyn belongs to a class of medications called mast cell stabilizers.

Is ketotifen an immunosuppressant?

Ketotifen is a second-generation antihistamine that exhibits anti-allergic, anti-asthma, anti-inflammatory, and immunosuppressive activities.

Is sodium cromoglycate still available?

Sodium cromoglicate (Intal®) CFC-free 5mg inhalers are out of stock until mid-November 2020. 2. Unlicensed supplies have been sourced in sufficient quantities to cover the out of stock period.

Is Montelukast the same as zafirlukast?

Montelukast works in a manner similar to zafirlukast (Accolate), blocking the binding of some leukotrienes to the cells that cause inflammation. Unlike zafirlukast, montelukast does not inhibit CYP2C9 or CYP3A4, two enzymes in the liver that are important in breaking down and eliminating many drugs.

Is Montelukast a mast cell stabilizer?

All three classes of drugs are commonly used in the prevention and treatment of mast cell activation-mediated disorders ranging from asthma to allergic rhinitis. Leukotriene antagonists such as montelukast are widely used in the management of chronic asthma (6).

What is difference between mast cell stabilizers and antihistamines?

Mast cell stabilizers have been proven as effective reducers of allergy signs and symptoms, but in recent years they are rarely used as exclusive single-acting treatment, but rather as dual-treatment with antihistamines, as a result of their slow activation (3–5 days).

What is the brand name for ipratropium bromide?

Ipratropium is available under the following different brand names: Atrovent, and Atrovent HFA.

What type of drug is ipratropium?

Ipratropium is in a class of medications called bronchodilators. It works by relaxing and opening the air passages to the lungs to make breathing easier.