What type of drug is FIRAZYR?

Firazyr is a prescription medicine used to treat the symptoms of hereditary Angioedema. Firazyr may be used alone or with other medications. Firazyr belongs to a class of drugs called Immunomodulators; Selective Bradykinin B2 Receptor Antagonists.

How fast does FIRAZYR work?

It takes approximately 45 minutes for Firazyr to reach peak levels in the blood. Firazyr has a short half-life (approximately 1.4 hours) and most of a dose is eliminated after 5.6 to 7 hours. There is no evidence of accumulation of Firazyr after three 30mg doses administered 6 hours apart.

What is FIRAZYR used for?

FIRAZYR is a medicine used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older.

How is FIRAZYR administered?

FIRAZYR is administered over at least 30 seconds into the abdominal area. Patients may self-administer FIRAZYR upon recognition of symptoms of an HAE attack, after training by a healthcare professional. FIRAZYR is available as a 3-mL, prefilled, single-use syringe (30 mg).

Is FIRAZYR a biologic?

Firazyr and Cinryze are both brand-name drugs. Firazyr is also available as a generic drug called icatibant. There isn’t currently a generic of Cinryze available because Cinryze is what’s known as a biologic drug.

Who manufactures FIRAZYR?

Shire plc (LSE: SHP,NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for FIRAZYR® (icatibant injection) for treatment of acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older.

Is firazyr a specialty drug?

It’s important to note that you’ll have to get Firazyr at a specialty pharmacy.

How do you take Firazyr?

Choose the injection site. The injection site should be a fold of skin on your stomach (abdomen), about 2 to 4 inches (5 to 10 cm) below your belly button on either side. The area you choose for injection should be at least 2 inches (5 cm) away from any scars. Do not choose an area that is bruised, swollen or painful.

How do you give FIRAZYR?

When do you use FIRAZYR?

FIRAZYR is used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. FIRAZYR is the first FDA-approved injection you give yourself under the skin (subcutaneously) to treat acute attacks of HAE—both in and out of the home—after you have been trained by a healthcare professional.

Is Firazyr a specialty drug?

Can kalbitor be self administered?

No, you shouldn’t self-inject Kalbitor. Kalbitor can cause a serious allergic reaction called anaphylaxis. * So only a healthcare professional should give you the injections. In fact, you’ll need to receive them in a medical setting where anaphylaxis and hereditary angioedema (HAE) can be treated.

Are there any side effects after taking Firazyr?

Injection site reactions are reported in most patients after administration of Firazyr. Other adverse reactions reported after administration of Firazyr include pyrexia, increase in transaminases, dizziness, and rash [see Adverse Reactions (6.1)].

What kind of syringe does Firazyr come in?

Firazyr is supplied as a single-use, prefilled syringe for subcutaneous administration. Each syringe delivers 3 mL of a sterile solution of icatibant 30 mg (as icatibant acetate). Each glass syringe has a bromobutyl plunger stopper, which is not made of latex natural rubber.

How many milligrams of Firazyr should I take?

Indications and Usage for Firazyr Firazyr® (icatibant) is indicated for the treatment of acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. The recommended dose of Firazyr is 30 mg administered by subcutaneous (SC) injection in the abdominal area.