Is Marburg a DNA or RNA virus?

Marburg virus disease (MVD) is a rare but severe hemorrhagic fever which affects both people and non-human primates. MVD is caused by the Marburg virus, a genetically unique zoonotic (or, animal-borne) RNA virus of the filovirus family.

What type of virus is Marburg?

What are the characteristics of Marburg virus?

Illness caused by Marburg virus begins abruptly, with high fever, severe headache and severe malaise. Muscle aches and pains are a common feature. Severe watery diarrhoea, abdominal pain and cramping, nausea and vomiting can begin on the third day. Diarrhoea can persist for a week.

What is the size of Marburg virus?

CHARACTERISTICS: Marburg virus is a member of the Filoviridae family, and is an elongated filamentous molecule, highly variable in length, but typically around 1000 nm long with a uniform diameter of 80 nm(2,3).

Is the Marburg virus enveloped?

Marburg virus (MARV) and the ebolaviruses are filamentous, enveloped, negative-sense, single-stranded RNA (ssRNA) viruses that belong to the family Filoviridae and can cause severe hemorrhagic fever in both humans and nonhuman primates.

What is the shape of the dengue virus?

The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid, which is made of the viral genome and C proteins. The nucleocapsid is surrounded by a membrane called the viral envelope, a lipid bilayer that is taken from the host.

What color is Marburg virus?

VP24 residues conserved across the filovirus family (Marburg and five ebolaviruses) are colored dark blue; those visible in this view are labeled.

How does Marburg virus replicate?

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation.

How is the structure of the Marburg virus revealed?

Marburg virus particles were imaged in 3-D in the act of budding from infected cells. Analyzing such images sheds light on the structure of the virus and the mechanisms by which it is assembled. When it comes to nasty pathogens, Marburg virus is among the nastiest.

What kind of shape does a virus have?

Virus capsids predominantly come in two shapes: helicaland icosahedral. The helix (plural: helices) is a spiral shape that curves cylindrically around an axis. It is also a common biological structure: many proteins have sections that have a helical shape, and DNA is a double-helix of nucleotides.

What kind of shape is an icosahedron virus?

An icosahedron is a geometric shape with 20 sides, each composed of an equilateral triangle, and icosahedral viruses increase the number of structural units in each face to expand capsid size.

What makes up the core of a virus?

At the core of the viral particle is the ribonucleoprotein complex, also called the nucleocapsid, which is made up of the viral RNA genome and its associated nucleocapsid proteins. The nucleocapsids are tubular structures that remain tightly associated with the RNA genome and give it its helical shape.